2021 Big 12 Conference Leaders Scoring Defense - Games in October Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 8 | 3 | 8 | 0 | 0 | 65 | 16.3 |
| 2 | Iowa State | 4 | 12 | 1 | 11 | 0 | 0 | 86 | 21.5 |
| 3 | Baylor | 4 | 11 | 5 | 11 | 0 | 0 | 92 | 23.0 |
| 4 | Kansas State | 4 | 11 | 9 | 11 | 0 | 1 | 106 | 26.5 |
| 5 | West Virginia | 4 | 14 | 6 | 14 | 0 | 0 | 116 | 29.0 |
| 6 | Oklahoma | 5 | 20 | 5 | 19 | 0 | 0 | 154 | 30.8 |
| 7 | Texas Tech | 5 | 21 | 5 | 20 | 0 | 1 | 163 | 32.6 |
| 8 | TCU | 5 | 21 | 10 | 19 | 0 | 0 | 175 | 35.0 |
| 9 | Texas | 4 | 16 | 11 | 14 | 1 | 0 | 145 | 36.3 |
| 10 | Kansas | 4 | 25 | 5 | 25 | 0 | 0 | 190 | 47.5 |