2021 Big 12 Conference Leaders Tackles For Loss - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Oklahoma State | 9 | 71.0 | 300 | 7.89 |
| 2 | Baylor | 8 | 64.0 | 292 | 8.00 |
| 3 | Oklahoma | 6 | 51.0 | 203 | 8.50 |
| 3 | Texas | 8 | 51.0 | 150 | 6.38 |
| 5 | West Virginia | 8 | 50.0 | 190 | 6.25 |
| 6 | Iowa State | 7 | 44.0 | 173 | 6.29 |
| 7 | Texas Tech | 7 | 38.0 | 156 | 5.43 |
| 8 | Kansas State | 6 | 37.0 | 139 | 6.17 |
| 9 | TCU | 7 | 29.0 | 97 | 4.14 |
| 10 | Kansas | 7 | 22.0 | 73 | 3.14 |