2021 Big 12 Conference Leaders Tackles For Loss - Games in October Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Oklahoma | 5 | 29.0 | 100 | 5.80 |
| 2 | Oklahoma State | 4 | 28.0 | 88 | 7.00 |
| 3 | Kansas State | 4 | 27.0 | 97 | 6.75 |
| 4 | Baylor | 4 | 26.0 | 133 | 6.50 |
| 5 | West Virginia | 4 | 22.0 | 96 | 5.50 |
| 5 | Texas | 4 | 22.0 | 80 | 5.50 |
| 7 | TCU | 5 | 20.0 | 89 | 4.00 |
| 7 | Iowa State | 4 | 20.0 | 63 | 5.00 |
| 9 | Texas Tech | 5 | 18.0 | 63 | 3.60 |
| 10 | Kansas | 4 | 14.0 | 42 | 3.50 |