2021 Big 12 Conference Leaders Penalties - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Kansas State | 3 | 13 | 108 | 4.3 | 36.0 |
| 2 | Kansas | 3 | 11 | 115 | 3.7 | 38.3 |
| 3 | West Virginia | 3 | 18 | 138 | 6.0 | 46.0 |
| 4 | Texas Tech | 4 | 22 | 186 | 5.5 | 46.5 |
| 5 | Oklahoma State | 4 | 22 | 205 | 5.5 | 51.3 |
| 6 | Iowa State | 5 | 25 | 210 | 5.0 | 42.0 |
| 7 | Baylor | 5 | 28 | 217 | 5.6 | 43.4 |
| 8 | Texas | 5 | 30 | 222 | 6.0 | 44.4 |
| 9 | Oklahoma | 3 | 29 | 235 | 9.7 | 78.3 |
| 10 | TCU | 3 | 34 | 291 | 11.3 | 97.0 |