2021 Big 12 Conference Leaders Penalties - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Kansas | 9 | 38 | 289 | 4.2 | 32.1 |
| 2 | Iowa State | 8 | 38 | 292 | 4.8 | 36.5 |
| 3 | West Virginia | 10 | 49 | 423 | 4.9 | 42.3 |
| 4 | Texas Tech | 9 | 45 | 394 | 5.0 | 43.8 |
| 5 | Kansas State | 10 | 57 | 481 | 5.7 | 48.1 |
| 6 | TCU | 9 | 51 | 446 | 5.7 | 49.6 |
| 7 | Oklahoma | 10 | 58 | 498 | 5.8 | 49.8 |
| 8 | Texas | 7 | 39 | 357 | 5.6 | 51.0 |
| 9 | Baylor | 9 | 47 | 460 | 5.2 | 51.1 |
| 10 | Oklahoma State | 10 | 62 | 566 | 6.2 | 56.6 |