2021 Big 12 Conference Leaders Total Offense - Games in August/September Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 4 | 640 | 1204 | 244 | 1844 | 7.56 | 461.0 |
| 2 | Oklahoma | 4 | 644 | 1131 | 284 | 1775 | 6.25 | 443.8 |
| 3 | Iowa State | 4 | 623 | 1023 | 270 | 1646 | 6.10 | 411.5 |
| 4 | West Virginia | 4 | 493 | 993 | 271 | 1486 | 5.48 | 371.5 |
| 5 | Oklahoma State | 4 | 573 | 906 | 284 | 1479 | 5.21 | 369.8 |
| 6 | Texas | 4 | 1071 | 879 | 269 | 1950 | 7.25 | 487.5 |
| 7 | Baylor | 4 | 1093 | 865 | 259 | 1958 | 7.56 | 489.5 |
| 8 | Kansas | 4 | 570 | 781 | 258 | 1351 | 5.24 | 337.8 |
| 9 | TCU | 3 | 619 | 763 | 201 | 1382 | 6.88 | 460.7 |
| 10 | Kansas State | 4 | 739 | 643 | 232 | 1382 | 5.96 | 345.5 |