2021 Big 12 Conference Leaders Total Offense - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 2 | 322 | 638 | 126 | 960 | 7.62 | 480.0 |
| 2 | Oklahoma State | 3 | 616 | 618 | 234 | 1234 | 5.27 | 411.3 |
| 3 | Texas | 2 | 597 | 458 | 130 | 1055 | 8.12 | 527.5 |
| 4 | Baylor | 2 | 547 | 379 | 144 | 926 | 6.43 | 463.0 |
| 5 | Oklahoma | 1 | 116 | 314 | 75 | 430 | 5.73 | 430.0 |
| 6 | Iowa State | 1 | 184 | 309 | 67 | 493 | 7.36 | 493.0 |
| 7 | TCU | 1 | 170 | 276 | 58 | 446 | 7.69 | 446.0 |
| 8 | Kansas | 1 | 172 | 238 | 68 | 410 | 6.03 | 410.0 |
| 9 | Kansas State | 1 | 269 | 129 | 61 | 398 | 6.52 | 398.0 |