2021 Big 12 Conference Leaders Total Offense - Games in December/January Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 2 | 300 | 634 | 182 | 934 | 5.13 | 467.0 |
| 2 | Baylor | 2 | 341 | 220 | 119 | 561 | 4.71 | 280.5 |
| 3 | Texas Tech | 1 | 260 | 252 | 72 | 512 | 7.11 | 512.0 |
| 4 | Oklahoma | 1 | 322 | 242 | 70 | 564 | 8.06 | 564.0 |
| 5 | Kansas State | 1 | 183 | 259 | 62 | 442 | 7.13 | 442.0 |
| 6 | Iowa State | 1 | 66 | 204 | 60 | 270 | 4.50 | 270.0 |
| 7 | West Virginia | 1 | 66 | 140 | 58 | 206 | 3.55 | 206.0 |