2021 Big 12 Conference Leaders Penalties - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Kansas | 10 | 36 | 310 | 3.6 | 31.0 |
| 2 | Texas Tech | 10 | 46 | 388 | 4.6 | 38.8 |
| 3 | Iowa State | 11 | 52 | 419 | 4.7 | 38.1 |
| 4 | Oklahoma State | 10 | 58 | 548 | 5.8 | 54.8 |
| 5 | Kansas State | 11 | 59 | 504 | 5.4 | 45.8 |
| 6 | Texas | 10 | 60 | 503 | 6.0 | 50.3 |
| 7 | West Virginia | 12 | 61 | 486 | 5.1 | 40.5 |
| 7 | Baylor | 11 | 61 | 546 | 5.5 | 49.6 |
| 9 | TCU | 10 | 71 | 631 | 7.1 | 63.1 |
| 10 | Oklahoma | 11 | 74 | 622 | 6.7 | 56.5 |