2021 Atlantic Coast Conference Leaders Total Offense - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sam Howell | N Carolina | JR | QB | 2 | 206 | 693 | 88 | 899 | 10.22 | 449.5 |
| 2 | Kenny Pickett | Pittsburgh | SR | QB | 2 | 96 | 654 | 83 | 750 | 9.04 | 375.0 |
| 3 | Sam Hartman | Wk Forest | SO | QB | 2 | 21 | 646 | 65 | 667 | 10.26 | 333.5 |
| 4 | Devin Leary | NC State | SO | QB | 2 | -7 | 483 | 67 | 476 | 7.10 | 238.0 |
| 5 | Malik Cunningham | Louisville | JR | QB | 2 | 165 | 472 | 84 | 637 | 7.58 | 318.5 |
| 6 | Brennan Armstrong | Virginia | JR | QB | 1 | 94 | 337 | 45 | 431 | 9.58 | 431.0 |
| 7 | Braxton Burmeister | Va Tech | JR | QB | 2 | 94 | 326 | 72 | 420 | 5.83 | 210.0 |
| 8 | Dennis Grosel | BC | SR | QB | 2 | 55 | 258 | 41 | 313 | 7.63 | 156.5 |
| 9 | Jordan Travis | FSU | SO | QB | 2 | 87 | 253 | 50 | 340 | 6.80 | 170.0 |
| 10 | DJ Uiagalelei | Clemson | SO | QB | 1 | -6 | 241 | 46 | 235 | 5.11 | 235.0 |
| 11 | Jordan Yates | Ga Tech | FR | QB | 2 | 47 | 231 | 66 | 278 | 4.21 | 139.0 |
| 11 | Jay Woolfolk | Virginia | FR | QB | 2 | 21 | 231 | 56 | 252 | 4.50 | 126.0 |
| 13 | Gunnar Holmberg | Duke | SR | QB | 1 | -5 | 228 | 38 | 223 | 5.87 | 223.0 |
| 14 | D'Eriq King | Miami (Fl) | SR | QB | 1 | 79 | 200 | 52 | 279 | 5.37 | 279.0 |
| 15 | Chubba Purdy | FSU | FR | QB | 1 | 5 | 98 | 6 | 103 | 17.17 | 103.0 |
| 16 | Tommy DeVito | Syracuse | JR | QB | 1 | 49 | 92 | 24 | 141 | 5.88 | 141.0 |
| 17 | Nick Patti | Pittsburgh | JR | QB | 2 | 9 | 91 | 9 | 100 | 11.11 | 50.0 |
| 18 | Garrett Shrader | Syracuse | SO | QB | 2 | 61 | 85 | 33 | 146 | 4.42 | 73.0 |
| 19 | Jacolby Criswell | N Carolina | SO | QB | 1 | 1 | 54 | 3 | 55 | 18.33 | 55.0 |
| 20 | McKenzie Milton | FSU | SR | QB | 1 | 6 | 48 | 10 | 54 | 5.40 | 54.0 |
| 21 | Davis Beville | Pittsburgh | SO | QB | 1 | 0 | 45 | 3 | 45 | 15.00 | 45.0 |
| 22 | Hunter Helms | Clemson | FR | QB | 1 | 4 | 42 | 9 | 46 | 5.11 | 46.0 |
| 23 | Taisun Phommachanh | Clemson | SO | QB | 1 | 16 | 33 | 4 | 49 | 12.25 | 49.0 |
| 24 | Braden Smith | Louisville | SO | WR | 2 | 0 | 32 | 2 | 32 | 16.00 | 16.0 |
| 25 | Billy Wiles | Clemson | FR | QB | 1 | 2 | 31 | 5 | 33 | 6.60 | 33.0 |
| 26 | Jeff Sims | Ga Tech | FR | QB | 1 | 34 | 23 | 15 | 57 | 3.80 | 57.0 |
| 27 | Phil Jurkovec | BC | JR | QB | 1 | 0 | 22 | 4 | 22 | 5.50 | 22.0 |
| 28 | Knox Kadum | Va Tech | FR | QB | 1 | 13 | 17 | 6 | 30 | 5.00 | 30.0 |
| 29 | Connor Blumrick | Va Tech | JR | QB | 2 | 67 | 3 | 12 | 70 | 5.83 | 35.0 |