2021 Atlantic Coast Conference Leaders Scoring Defense - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 7 | 14 | 6 | 13 | 0 | 0 | 115 | 16.4 |
| 2 | North Carolina State | 5 | 16 | 3 | 16 | 0 | 0 | 121 | 24.2 |
| 3 | Boston College | 6 | 16 | 6 | 15 | 0 | 0 | 129 | 21.5 |
| 4 | Florida State | 5 | 17 | 6 | 13 | 2 | 0 | 137 | 27.4 |
| 5 | Pittsburgh | 7 | 20 | 5 | 18 | 1 | 1 | 157 | 22.4 |
| 6 | Syracuse | 5 | 18 | 11 | 17 | 1 | 0 | 160 | 32.0 |
| 7 | Miami (Florida) | 5 | 19 | 10 | 18 | 1 | 0 | 164 | 32.8 |
| 8 | Virginia Tech | 6 | 22 | 8 | 21 | 0 | 0 | 177 | 29.5 |
| 9 | Louisville | 6 | 22 | 11 | 19 | 0 | 0 | 184 | 30.7 |
| 10 | Georgia Tech | 6 | 25 | 8 | 23 | 1 | 0 | 199 | 33.2 |
| 11 | North Carolina | 6 | 25 | 11 | 21 | 2 | 0 | 208 | 34.7 |
| 12 | Duke | 5 | 27 | 7 | 27 | 0 | 0 | 210 | 42.0 |
| 13 | Virginia | 5 | 30 | 8 | 30 | 0 | 0 | 234 | 46.8 |
| 14 | Wake Forest | 8 | 36 | 10 | 35 | 0 | 0 | 281 | 35.1 |