2021 Atlantic Coast Conference Leaders Opponent Penalties - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Wake Forest | 8 | 58 | 527 | 7.3 | 65.9 |
| 2 | Clemson | 7 | 56 | 506 | 8.0 | 72.3 |
| 3 | Miami (Florida) | 5 | 43 | 432 | 8.6 | 86.4 |
| 4 | Pittsburgh | 7 | 49 | 427 | 7.0 | 61.0 |
| 5 | Florida State | 5 | 44 | 361 | 8.8 | 72.2 |
| 6 | Boston College | 6 | 44 | 360 | 7.3 | 60.0 |
| 7 | Virginia Tech | 6 | 35 | 326 | 5.8 | 54.3 |
| 8 | Louisville | 6 | 36 | 305 | 6.0 | 50.8 |
| 9 | Virginia | 5 | 35 | 300 | 7.0 | 60.0 |
| 10 | Duke | 5 | 37 | 295 | 7.4 | 59.0 |
| 10 | Georgia Tech | 6 | 31 | 295 | 5.2 | 49.2 |
| 12 | North Carolina | 6 | 30 | 236 | 5.0 | 39.3 |
| 13 | North Carolina State | 5 | 28 | 213 | 5.6 | 42.6 |
| 14 | Syracuse | 5 | 19 | 156 | 3.8 | 31.2 |