2021 Atlantic Coast Conference Leaders Opponent Penalties - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 1 | 11 | 70 | 11.0 | 70.0 |
| 2 | Duke | 1 | 9 | 65 | 9.0 | 65.0 |
| 3 | Pittsburgh | 2 | 17 | 183 | 8.5 | 91.5 |
| 4 | Boston College | 2 | 16 | 116 | 8.0 | 58.0 |
| 5 | Wake Forest | 2 | 15 | 120 | 7.5 | 60.0 |
| 6 | North Carolina State | 2 | 14 | 132 | 7.0 | 66.0 |
| 6 | Georgia Tech | 2 | 14 | 114 | 7.0 | 57.0 |
| 8 | Virginia Tech | 2 | 13 | 132 | 6.5 | 66.0 |
| 8 | Florida State | 2 | 13 | 99 | 6.5 | 49.5 |
| 10 | Miami (Florida) | 1 | 6 | 48 | 6.0 | 48.0 |
| 11 | Louisville | 2 | 10 | 90 | 5.0 | 45.0 |
| 11 | Virginia | 2 | 10 | 87 | 5.0 | 43.5 |
| 11 | North Carolina | 2 | 10 | 79 | 5.0 | 39.5 |
| 14 | Syracuse | 2 | 7 | 69 | 3.5 | 34.5 |