2021 Atlantic Coast Conference Leaders Interceptions - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 6 | 9 | 182 | 2 | 1.50 |
| 2 | Florida State | 5 | 6 | 52 | 0 | 1.20 |
| 3 | North Carolina | 7 | 7 | 61 | 0 | 1.00 |
| 3 | Wake Forest | 4 | 4 | 83 | 1 | 1.00 |
| 3 | North Carolina State | 4 | 4 | 5 | 0 | 1.00 |
| 6 | Clemson | 6 | 5 | 21 | 1 | 0.83 |
| 7 | Virginia Tech | 5 | 3 | 70 | 1 | 0.60 |
| 7 | Miami (Florida) | 5 | 3 | 39 | 0 | 0.60 |
| 7 | Virginia | 5 | 3 | 33 | 0 | 0.60 |
| 10 | Syracuse | 5 | 2 | 9 | 0 | 0.40 |
| 11 | Boston College | 3 | 1 | 0 | 0 | 0.33 |
| 12 | Louisville | 7 | 2 | 95 | 1 | 0.29 |