2021 Atlantic Coast Conference Leaders Sacks - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Pittsburgh | 6 | 20.0 | 149 | 3.33 |
| 2 | North Carolina | 7 | 19.0 | 127 | 2.71 |
| 3 | Clemson | 6 | 16.0 | 93 | 2.67 |
| 3 | Florida State | 5 | 16.0 | 86 | 3.20 |
| 5 | Syracuse | 5 | 14.0 | 91 | 2.80 |
| 6 | Louisville | 7 | 13.0 | 82 | 1.86 |
| 7 | Miami (Florida) | 5 | 10.0 | 82 | 2.00 |
| 7 | North Carolina State | 4 | 10.0 | 42 | 2.50 |
| 9 | Virginia | 5 | 7.0 | 46 | 1.40 |
| 10 | Wake Forest | 4 | 6.0 | 57 | 1.50 |
| 10 | Georgia Tech | 6 | 6.0 | 37 | 1.00 |
| 10 | Virginia Tech | 5 | 6.0 | 34 | 1.20 |
| 13 | Boston College | 3 | 5.0 | 17 | 1.67 |
| 13 | Duke | 3 | 5.0 | 15 | 1.67 |