2021 American Athletic Conference Leaders Total Offense - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jerome Ford | Cincinnati | JR | RB | 2 | 264 | 0 | 33 | 264 | 8.00 | 132.0 |
| 2 | Davis Brin | Tulsa | JR | QB | 1 | 18 | 285 | 39 | 303 | 7.77 | 303.0 |
| 3 | Clayton Tune | Houston | JR | QB | 2 | 64 | 533 | 96 | 597 | 6.22 | 298.5 |
| 4 | Tai Lavatai | Navy | SO | QB | 1 | 62 | 82 | 26 | 144 | 5.54 | 144.0 |
| 5 | Anthony Watkins | Tulsa | SO | RB | 1 | 55 | 0 | 10 | 55 | 5.50 | 55.0 |
| 6 | Desmond Ridder | Cincinnati | SR | QB | 2 | 13 | 334 | 66 | 347 | 5.26 | 173.5 |
| 7 | Mikey Keene | UCF | FR | QB | 1 | -19 | 144 | 25 | 125 | 5.00 | 125.0 |
| 8 | Isaiah Bowser | UCF | SR | RB | 1 | 155 | 0 | 35 | 155 | 4.43 | 155.0 |
| 9 | Alton McCaskill | Houston | FR | RB | 2 | 117 | 0 | 27 | 117 | 4.33 | 58.5 |
| 10 | Shamari Brooks | Tulsa | SR | RB | 1 | 107 | 0 | 26 | 107 | 4.12 | 107.0 |
| 11 | Deneric Prince | Tulsa | JR | RB | 1 | 44 | 0 | 11 | 44 | 4.00 | 44.0 |
| 12 | Carlinos Acie | Navy | SR | SB | 1 | 34 | 0 | 9 | 34 | 3.78 | 34.0 |
| 13 | Isaac Ruoss | Navy | SR | FB | 1 | 33 | 0 | 9 | 33 | 3.67 | 33.0 |
Note: To qualify, player must have played in 75% of his team's games and have a minimum of 9.0 plays per game played.