2021 American Athletic Conference Leaders Interceptions - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Kevin Henry | Tulane | SR | LB | 1 | 1 | 49 | 1 | 1.00 |
| 1 | Bryan Massey | SMU | SO | S | 1 | 1 | 48 | 0 | 1.00 |
| 1 | Ja'Quan McMillian | ECU | SO | CB | 1 | 1 | 23 | 1 | 1.00 |
| 1 | Derrion Rakestraw | Tulane | SR | S | 1 | 1 | 12 | 0 | 1.00 |
| 1 | Ja'von Hicks | Cincinnati | SR | S | 1 | 1 | 11 | 0 | 1.00 |
| 1 | Trevor Denbow | SMU | SR | S | 1 | 1 | 7 | 0 | 1.00 |
| 1 | Manny Walker | Temple | SR | DE | 1 | 1 | 4 | 0 | 1.00 |
| 1 | Arquon Bush | Cincinnati | JR | CB | 1 | 1 | 2 | 0 | 1.00 |
| 1 | Isaiah Nwokobia | SMU | FR | S | 1 | 1 | 2 | 0 | 1.00 |
| 1 | Sylvonta Oliver | Memphis | SR | DB | 1 | 1 | 1 | 0 | 1.00 |
| 1 | Tatum Bethune | UCF | JR | LB | 1 | 1 | 0 | 0 | 1.00 |
| 1 | Ahmad Gardner | Cincinnati | JR | CB | 1 | 1 | 0 | 0 | 1.00 |