2021 Big Ten Conference Leaders Long All Purpose Plays - Games in November Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Braelon Allen | Wisconsin | FR | RB | 4 | 6 | 2 | 2 | 1 | 1 | 0 | 0 |
| 1 | David Bell | Purdue | JR | WR | 4 | 3 | 3 | 2 | 0 | 0 | 0 | 0 |
| 1 | Charlie Jones | Iowa | SR | WR | 4 | 3 | 2 | 2 | 2 | 2 | 1 | 1 |
| 1 | Samori Toure | Nebraska | SR | WR | 3 | 3 | 3 | 2 | 1 | 1 | 0 | 0 |
| 1 | Garrett Wilson | Ohio State | JR | WR | 3 | 2 | 2 | 2 | 1 | 1 | 0 | 0 |
| 1 | Milton Wright | Purdue | JR | WR | 4 | 3 | 3 | 2 | 0 | 0 | 0 | 0 |
| 7 | Chris Autman-Bell | Minnesota | SR | WR | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 7 | Stephan Bracey | Wisconsin | SO | WR | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 7 | Ji'Ayir Brown | Penn State | SR | S | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 7 | Blake Corum | Michigan | SO | RB | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 7 | Danny Davis III | Wisconsin | SR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 7 | Jahan Dotson | Penn State | SR | WR | 4 | 5 | 2 | 1 | 1 | 1 | 1 | 0 |
| 7 | Donovan Edwards | Michigan | FR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 7 | Montorie Foster | Mich St | SO | WR | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 7 | Tyler Goodson | Iowa | JR | RB | 4 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 7 | Hassan Haskins | Michigan | SR | RB | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 7 | TreVeyon Henderson | Ohio State | FR | RB | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 7 | Cornelius Johnson | Michigan | JR | WR | 4 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 7 | Malick Meiga | Penn State | FR | WR | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 7 | Bo Melton | Rutgers | SR | WR | 4 | 4 | 1 | 1 | 0 | 0 | 0 | 0 |
| 7 | Jaxon Smith-Njigba | Ohio State | SO | WR | 4 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 7 | Casey Washington | Illinois | SO | WR | 3 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |