2021 Big Ten Conference Leaders Scoring Defense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Nebraska | 3 | 4 | 1 | 4 | 1 | 0 | 33 | 11.0 |
| 2 | Minnesota | 4 | 6 | 2 | 4 | 0 | 0 | 46 | 11.5 |
| 2 | Indiana | 3 | 11 | 2 | 9 | 1 | 0 | 83 | 27.7 |
| 4 | Northwestern | 3 | 5 | 3 | 3 | 0 | 0 | 42 | 14.0 |
| 4 | Iowa | 4 | 7 | 3 | 7 | 0 | 0 | 58 | 14.5 |
| 4 | Purdue | 4 | 12 | 3 | 12 | 0 | 0 | 93 | 23.3 |
| 4 | Ohio State | 4 | 14 | 3 | 14 | 0 | 0 | 107 | 26.8 |
| 4 | Illinois | 3 | 12 | 3 | 12 | 0 | 0 | 93 | 31.0 |
| 9 | Michigan | 4 | 8 | 4 | 8 | 0 | 0 | 68 | 17.0 |
| 9 | Wisconsin | 4 | 9 | 4 | 9 | 0 | 0 | 75 | 18.8 |
| 9 | Michigan State | 4 | 10 | 4 | 9 | 1 | 0 | 83 | 20.8 |
| 12 | Maryland | 4 | 5 | 5 | 5 | 0 | 0 | 50 | 12.5 |
| 12 | Rutgers | 4 | 8 | 5 | 7 | 1 | 0 | 72 | 18.0 |
| 14 | Penn State | 4 | 8 | 6 | 8 | 0 | 0 | 74 | 18.5 |