2021 Big Ten Conference Leaders Passing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Purdue | 4 | 132 | 83 | 62.9 | 1055 | 8.0 | 9 | 5 | 144.93 | 33.0 | 263.8 |
| 2 | Indiana | 5 | 156 | 91 | 58.3 | 1071 | 6.9 | 8 | 4 | 127.79 | 31.2 | 214.2 |
| 2 | Penn State | 5 | 144 | 91 | 63.2 | 1083 | 7.5 | 8 | 4 | 139.14 | 28.8 | 216.6 |
| 2 | Nebraska | 5 | 177 | 109 | 61.6 | 1235 | 7.0 | 4 | 4 | 123.13 | 35.4 | 247.0 |
| 5 | Iowa | 2 | 56 | 35 | 62.5 | 483 | 8.6 | 3 | 3 | 141.92 | 28.0 | 241.5 |
| 5 | Michigan | 4 | 148 | 93 | 62.8 | 1096 | 7.4 | 6 | 3 | 134.37 | 37.0 | 274.0 |
| 5 | Michigan State | 3 | 114 | 83 | 72.8 | 1025 | 9.0 | 10 | 3 | 172.02 | 38.0 | 341.7 |
| 8 | Illinois | 1 | 18 | 6 | 33.3 | 83 | 4.6 | 0 | 1 | 60.95 | 18.0 | 83.0 |
| 8 | Ohio State | 4 | 117 | 66 | 56.4 | 821 | 7.0 | 6 | 1 | 130.56 | 29.3 | 205.3 |
| 8 | Wisconsin | 3 | 92 | 51 | 55.4 | 624 | 6.8 | 5 | 1 | 128.19 | 30.7 | 208.0 |
| 8 | Minnesota | 2 | 46 | 24 | 52.2 | 500 | 10.9 | 6 | 1 | 182.17 | 23.0 | 250.0 |
| 8 | Rutgers | 4 | 109 | 66 | 60.6 | 1139 | 10.4 | 11 | 1 | 179.80 | 27.3 | 284.8 |
| 8 | Maryland | 4 | 146 | 100 | 68.5 | 1354 | 9.3 | 15 | 1 | 178.92 | 36.5 | 338.5 |
| 14 | Northwestern | 3 | 90 | 58 | 64.4 | 524 | 5.8 | 1 | 0 | 117.01 | 30.0 | 174.7 |