2021 Big Ten Conference Leaders Passing Defense - Games in December/January Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Iowa | 2 | 56 | 35 | 62.5 | 483 | 8.6 | 3 | 3 | 141.92 | 28.0 | 241.5 |
| 2 | Penn State | 1 | 20 | 14 | 70.0 | 98 | 4.9 | 0 | 2 | 91.16 | 20.0 | 98.0 |
| 3 | Minnesota | 1 | 31 | 18 | 58.1 | 140 | 4.5 | 0 | 1 | 89.55 | 31.0 | 140.0 |
| 3 | Wisconsin | 1 | 21 | 11 | 52.4 | 159 | 7.6 | 0 | 1 | 106.46 | 21.0 | 159.0 |
| 3 | Michigan State | 1 | 23 | 16 | 69.6 | 170 | 7.4 | 1 | 1 | 137.30 | 23.0 | 170.0 |
| 3 | Michigan | 2 | 69 | 40 | 58.0 | 506 | 7.3 | 4 | 1 | 135.80 | 34.5 | 253.0 |
| 7 | Maryland | 1 | 19 | 11 | 57.9 | 137 | 7.2 | 0 | 0 | 118.47 | 19.0 | 137.0 |
| 7 | Ohio State | 1 | 24 | 19 | 79.2 | 237 | 9.9 | 3 | 0 | 203.37 | 24.0 | 237.0 |
| 7 | Rutgers | 1 | 39 | 23 | 59.0 | 304 | 7.8 | 3 | 0 | 149.83 | 39.0 | 304.0 |
| 7 | Purdue | 1 | 42 | 26 | 61.9 | 378 | 9.0 | 5 | 0 | 176.80 | 42.0 | 378.0 |