2021 Big Ten Conference Leaders Opponent First Downs - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 6 | 22 | 50 | 11 | 83 | 13.8 |
| 2 | Illinois | 5 | 32 | 56 | 11 | 99 | 19.8 |
| 3 | Minnesota | 6 | 36 | 46 | 4 | 86 | 14.3 |
| 4 | Nebraska | 5 | 42 | 40 | 6 | 88 | 17.6 |
| 5 | Rutgers | 7 | 48 | 60 | 19 | 127 | 18.1 |
| 5 | Indiana | 6 | 48 | 77 | 11 | 136 | 22.7 |
| 7 | Michigan | 7 | 53 | 67 | 7 | 127 | 18.1 |
| 7 | Ohio State | 6 | 53 | 51 | 15 | 119 | 19.8 |
| 9 | Michigan State | 7 | 54 | 101 | 15 | 170 | 24.3 |
| 10 | Iowa | 7 | 55 | 67 | 12 | 134 | 19.1 |
| 11 | Maryland | 6 | 57 | 59 | 15 | 131 | 21.8 |
| 12 | Purdue | 7 | 63 | 68 | 12 | 143 | 20.4 |
| 13 | Penn State | 6 | 65 | 64 | 15 | 144 | 24.0 |
| 14 | Northwestern | 6 | 68 | 70 | 8 | 146 | 24.3 |