2021 Big Ten Conference Leaders Passes Defended - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Ohio State | 9 | 8 | 38 | 46 | 5.11 |
| 1 | Michigan | 10 | 7 | 38 | 45 | 4.50 |
| 3 | Michigan State | 9 | 6 | 36 | 42 | 4.67 |
| 4 | Penn State | 9 | 9 | 35 | 44 | 4.89 |
| 5 | Maryland | 9 | 3 | 33 | 36 | 4.00 |
| 6 | Iowa | 10 | 21 | 31 | 52 | 5.20 |
| 6 | Wisconsin | 9 | 14 | 31 | 45 | 5.00 |
| 6 | Nebraska | 9 | 6 | 31 | 37 | 4.11 |
| 9 | Illinois | 9 | 7 | 30 | 37 | 4.11 |
| 10 | Purdue | 9 | 11 | 29 | 40 | 4.44 |
| 10 | Indiana | 9 | 4 | 29 | 33 | 3.67 |
| 12 | Rutgers | 9 | 4 | 27 | 31 | 3.44 |
| 13 | Northwestern | 9 | 3 | 23 | 26 | 2.89 |
| 14 | Minnesota | 9 | 5 | 21 | 26 | 2.89 |