2021 Big Ten Conference Leaders Passes Defended - Games in October Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Michigan State | 4 | 3 | 21 | 24 | 6.00 |
| 2 | Wisconsin | 5 | 4 | 19 | 23 | 4.60 |
| 3 | Michigan | 4 | 5 | 18 | 23 | 5.75 |
| 4 | Penn State | 4 | 4 | 17 | 21 | 5.25 |
| 5 | Indiana | 4 | 3 | 13 | 16 | 4.00 |
| 5 | Nebraska | 4 | 3 | 13 | 16 | 4.00 |
| 5 | Minnesota | 4 | 1 | 13 | 14 | 3.50 |
| 5 | Rutgers | 4 | 1 | 13 | 14 | 3.50 |
| 5 | Maryland | 4 | 0 | 13 | 13 | 3.25 |
| 10 | Purdue | 4 | 8 | 12 | 20 | 5.00 |
| 10 | Ohio State | 4 | 6 | 12 | 18 | 4.50 |
| 10 | Illinois | 4 | 2 | 12 | 14 | 3.50 |
| 13 | Northwestern | 4 | 1 | 11 | 12 | 3.00 |
| 14 | Iowa | 4 | 10 | 10 | 20 | 5.00 |