2021 Big Ten Conference Leaders Interceptions - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Nebraska | 3 | 4 | 33 | 0 | 1.33 |
| 2 | Penn State | 4 | 5 | 30 | 1 | 1.25 |
| 3 | Ohio State | 4 | 4 | 150 | 2 | 1.00 |
| 3 | Michigan State | 4 | 4 | 78 | 1 | 1.00 |
| 3 | Iowa | 4 | 4 | 47 | 0 | 1.00 |
| 3 | Northwestern | 3 | 3 | 26 | 0 | 1.00 |
| 7 | Rutgers | 4 | 3 | 67 | 1 | 0.75 |
| 7 | Minnesota | 4 | 3 | 28 | 0 | 0.75 |
| 7 | Maryland | 4 | 3 | 5 | 0 | 0.75 |
| 10 | Illinois | 3 | 2 | 2 | 0 | 0.67 |
| 11 | Purdue | 4 | 2 | 9 | 0 | 0.50 |
| 11 | Wisconsin | 4 | 2 | 6 | 0 | 0.50 |
| 13 | Indiana | 3 | 1 | 0 | 0 | 0.33 |
| 14 | Michigan | 4 | 1 | 27 | 0 | 0.25 |