2021 Big Ten Conference Leaders Passes Defended - Games Lost Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Nebraska | 9 | 6 | 34 | 40 | 4.44 |
| 2 | Indiana | 10 | 5 | 32 | 37 | 3.70 |
| 2 | Illinois | 7 | 5 | 23 | 28 | 4.00 |
| 2 | Penn State | 6 | 5 | 19 | 24 | 4.00 |
| 5 | Northwestern | 9 | 4 | 24 | 28 | 3.11 |
| 6 | Iowa | 4 | 3 | 9 | 12 | 3.00 |
| 7 | Rutgers | 8 | 2 | 26 | 28 | 3.50 |
| 7 | Wisconsin | 4 | 2 | 12 | 14 | 3.50 |
| 7 | Minnesota | 4 | 2 | 10 | 12 | 3.00 |
| 7 | Michigan | 2 | 2 | 8 | 10 | 5.00 |
| 11 | Maryland | 6 | 1 | 15 | 16 | 2.67 |
| 11 | Ohio State | 2 | 1 | 11 | 12 | 6.00 |
| 11 | Michigan State | 2 | 1 | 5 | 6 | 3.00 |
| 14 | Purdue | 4 | 0 | 10 | 10 | 2.50 |