2021 Big Ten Conference Leaders Passes Defended - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Iowa | 7 | 16 | 22 | 38 | 5.43 |
| 2 | Purdue | 7 | 10 | 21 | 31 | 4.43 |
| 3 | Wisconsin | 6 | 8 | 21 | 29 | 4.83 |
| 4 | Penn State | 6 | 7 | 15 | 22 | 3.67 |
| 5 | Michigan State | 7 | 6 | 27 | 33 | 4.71 |
| 5 | Michigan | 7 | 6 | 22 | 28 | 4.00 |
| 5 | Illinois | 5 | 6 | 17 | 23 | 4.60 |
| 8 | Ohio State | 6 | 5 | 18 | 23 | 3.83 |
| 9 | Minnesota | 6 | 4 | 23 | 27 | 4.50 |
| 10 | Rutgers | 7 | 3 | 28 | 31 | 4.43 |
| 10 | Maryland | 6 | 3 | 22 | 25 | 4.17 |
| 10 | Northwestern | 6 | 3 | 17 | 20 | 3.33 |
| 10 | Nebraska | 5 | 3 | 13 | 16 | 3.20 |
| 14 | Indiana | 6 | 2 | 18 | 20 | 3.33 |