2021 Mid-American Conference Leaders Rushing Defense - All Games through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Toledo | 13 | 525 | 1969 | 3.75 | 11 | 40.38 | 151.46 |
| 2 | Western Michigan | 13 | 420 | 1886 | 4.49 | 17 | 32.31 | 145.08 |
| 3 | Central Michigan | 13 | 463 | 1551 | 3.35 | 18 | 35.62 | 119.31 |
| 3 | Miami (Ohio) | 13 | 482 | 1897 | 3.94 | 18 | 37.08 | 145.92 |
| 5 | Ball State | 13 | 528 | 2293 | 4.34 | 22 | 40.62 | 176.38 |
| 6 | Ohio | 12 | 478 | 2316 | 4.85 | 25 | 39.83 | 193.00 |
| 7 | Buffalo | 12 | 489 | 2339 | 4.78 | 27 | 40.75 | 194.92 |
| 7 | Eastern Michigan | 13 | 508 | 2599 | 5.12 | 27 | 39.08 | 199.92 |
| 9 | Bowling Green | 12 | 542 | 2254 | 4.16 | 30 | 45.17 | 187.83 |
| 10 | Akron | 12 | 482 | 2987 | 6.20 | 32 | 40.17 | 248.92 |
| 11 | Northern Illinois | 14 | 517 | 3003 | 5.81 | 33 | 36.93 | 214.50 |
| 12 | Kent State | 14 | 579 | 2882 | 4.98 | 40 | 41.36 | 205.86 |