2021 Mid-American Conference Leaders Rushing Defense - In The 4th Quarter through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Miami (Ohio) | 13 | 120 | 458 | 3.82 | 4 | 46 | 28 | 14 | 4 |
| 2 | Central Michigan | 13 | 107 | 467 | 4.36 | 5 | 69 | 24 | 16 | 6 |
| 3 | Western Michigan | 13 | 121 | 484 | 4.00 | 7 | 44 | 31 | 18 | 6 |
| 4 | Toledo | 13 | 136 | 503 | 3.70 | 3 | 34 | 28 | 16 | 5 |
| 5 | Ohio | 12 | 137 | 542 | 3.96 | 7 | 25 | 32 | 18 | 2 |
| 6 | Ball State | 13 | 141 | 555 | 3.94 | 3 | 46 | 32 | 14 | 1 |
| 7 | Bowling Green | 12 | 139 | 557 | 4.01 | 6 | 37 | 34 | 19 | 2 |
| 8 | Buffalo | 12 | 124 | 570 | 4.60 | 9 | 77 | 31 | 21 | 6 |
| 9 | Eastern Michigan | 13 | 138 | 592 | 4.29 | 8 | 33 | 38 | 18 | 4 |
| 10 | Northern Illinois | 14 | 134 | 641 | 4.78 | 6 | 36 | 36 | 25 | 7 |
| 11 | Akron | 12 | 124 | 686 | 5.53 | 7 | 32 | 39 | 24 | 5 |
| 12 | Kent State | 14 | 161 | 802 | 4.98 | 16 | 80 | 40 | 21 | 10 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||