2021 Mid-American Conference Leaders Passing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Toledo | 1 | 36 | 24 | 66.7 | 317 | 8.8 | 3 | 1 | 162.58 | 36.0 | 317.0 |
| 2 | Akron | 1 | 26 | 18 | 69.2 | 385 | 14.8 | 2 | 1 | 211.31 | 26.0 | 385.0 |
| 3 | Kent State | 1 | 37 | 26 | 70.3 | 212 | 5.7 | 1 | 0 | 127.32 | 37.0 | 212.0 |
| 4 | Northern Illinois | 1 | 17 | 12 | 70.6 | 233 | 13.7 | 1 | 0 | 205.13 | 17.0 | 233.0 |
| 5 | Ohio | 1 | 34 | 25 | 73.5 | 252 | 7.4 | 2 | 1 | 149.32 | 34.0 | 252.0 |
| 6 | Western Michigan | 2 | 51 | 38 | 74.5 | 631 | 12.4 | 9 | 1 | 232.76 | 25.5 | 315.5 |
| 7 | Miami (Ohio) | 1 | 26 | 20 | 76.9 | 295 | 11.3 | 4 | 2 | 207.62 | 26.0 | 295.0 |