2021 Mid-American Conference Leaders Opponent First Downs - Games in August/September Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Eastern Michigan | 4 | 44 | 38 | 4 | 86 | 21.5 |
| 1 | Akron | 4 | 40 | 43 | 4 | 87 | 21.8 |
| 1 | Northern Illinois | 4 | 53 | 33 | 4 | 90 | 22.5 |
| 4 | Central Michigan | 4 | 21 | 44 | 5 | 70 | 17.5 |
| 4 | Ball State | 4 | 37 | 45 | 5 | 87 | 21.8 |
| 6 | Kent State | 4 | 40 | 47 | 7 | 94 | 23.5 |
| 7 | Western Michigan | 4 | 31 | 23 | 8 | 62 | 15.5 |
| 7 | Miami (Ohio) | 4 | 41 | 26 | 8 | 75 | 18.8 |
| 9 | Buffalo | 4 | 34 | 31 | 9 | 74 | 18.5 |
| 10 | Toledo | 4 | 30 | 37 | 10 | 77 | 19.3 |
| 10 | Ohio | 4 | 54 | 38 | 10 | 102 | 25.5 |
| 12 | Bowling Green | 4 | 45 | 26 | 12 | 83 | 20.8 |