2021 Mid-American Conference Leaders Opponent First Downs - Games in October Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Toledo | 4 | 25 | 33 | 7 | 65 | 16.3 |
| 2 | Western Michigan | 4 | 36 | 36 | 3 | 75 | 18.8 |
| 3 | Northern Illinois | 4 | 25 | 46 | 6 | 77 | 19.3 |
| 4 | Miami (Ohio) | 4 | 22 | 53 | 7 | 82 | 20.5 |
| 5 | Ball State | 4 | 34 | 44 | 8 | 86 | 21.5 |
| 6 | Buffalo | 5 | 61 | 37 | 10 | 108 | 21.6 |
| 7 | Eastern Michigan | 4 | 41 | 43 | 6 | 90 | 22.5 |
| 7 | Akron | 4 | 54 | 33 | 3 | 90 | 22.5 |
| 9 | Central Michigan | 4 | 44 | 40 | 9 | 93 | 23.3 |
| 10 | Ohio | 4 | 39 | 48 | 8 | 95 | 23.8 |
| 11 | Bowling Green | 5 | 67 | 47 | 12 | 126 | 25.2 |
| 12 | Kent State | 4 | 46 | 54 | 13 | 113 | 28.3 |