2021 Pac-12 Conference Leaders First Downs - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Utah | 9 | 111 | 102 | 22 | 235 | 26.1 |
| 2 | USC | 9 | 82 | 119 | 29 | 230 | 25.6 |
| 3 | Oregon | 10 | 122 | 97 | 17 | 236 | 23.6 |
| 4 | Oregon State | 10 | 137 | 81 | 15 | 233 | 23.3 |
| 5 | UCLA | 10 | 126 | 91 | 13 | 230 | 23.0 |
| 6 | Arizona | 8 | 68 | 77 | 20 | 165 | 20.6 |
| 7 | Arizona State | 11 | 123 | 84 | 14 | 221 | 20.1 |
| 7 | Washington State | 9 | 71 | 97 | 13 | 181 | 20.1 |
| 9 | Washington | 10 | 72 | 99 | 19 | 190 | 19.0 |
| 10 | California | 11 | 92 | 99 | 15 | 206 | 18.7 |
| 11 | Stanford | 9 | 41 | 93 | 22 | 156 | 17.3 |
| 12 | Colorado | 10 | 77 | 49 | 19 | 145 | 14.5 |