2021 Pac-12 Conference Leaders First Downs - Games in August/September Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | USC | 4 | 36 | 53 | 14 | 103 | 25.8 |
| 2 | Oregon State | 4 | 50 | 41 | 6 | 97 | 24.3 |
| 3 | Arizona State | 4 | 48 | 39 | 8 | 95 | 23.8 |
| 4 | Oregon | 4 | 39 | 41 | 11 | 91 | 22.8 |
| 5 | Washington | 4 | 24 | 54 | 10 | 88 | 22.0 |
| 6 | Arizona | 4 | 34 | 43 | 9 | 86 | 21.5 |
| 7 | California | 4 | 35 | 41 | 8 | 84 | 21.0 |
| 7 | Washington State | 4 | 30 | 47 | 7 | 84 | 21.0 |
| 7 | Utah | 4 | 30 | 42 | 12 | 84 | 21.0 |
| 10 | UCLA | 4 | 44 | 35 | 1 | 80 | 20.0 |
| 11 | Stanford | 4 | 16 | 37 | 10 | 63 | 15.8 |
| 12 | Colorado | 4 | 38 | 15 | 7 | 60 | 15.0 |