2021 National Leaders Passes Defended - Games vs. Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Josh Wallace | U Mass | SO | CB | 4 | 0 | 8 | 8 | 2.00 |
| 1 | D.J. McCullough | NMSU | JR | DB | 1 | 0 | 2 | 2 | 2.00 |
| 3 | Roger McCreary | Auburn | SR | CB | 8 | 0 | 13 | 13 | 1.63 |
| 4 | Roger Cray | ODU | SR | CB | 7 | 1 | 10 | 11 | 1.57 |
| 5 | Marcus Jones | Houston | SR | CB | 9 | 5 | 9 | 14 | 1.56 |
| 5 | Trenton Thompson | SDSU | SR | S | 9 | 3 | 11 | 14 | 1.56 |
| 7 | Donte Kent | CMU | FR | DB | 8 | 0 | 12 | 12 | 1.50 |
| 7 | Duron Lowe | Liberty | SR | CB | 2 | 1 | 2 | 3 | 1.50 |
| 9 | Cortez Davis | Hawai'i | SR | DB | 8 | 1 | 10 | 11 | 1.38 |
| 9 | Samuel Womack | Toledo | SR | CB | 8 | 0 | 11 | 11 | 1.38 |
| 11 | Dy'vonne Inyang | UTEP | SR | DB | 6 | 2 | 6 | 8 | 1.33 |
| 11 | Nehemiah Shelton | SJSU | SR | CB | 6 | 1 | 7 | 8 | 1.33 |
| 13 | Quincy Riley | MTSU | FR | CB | 7 | 4 | 5 | 9 | 1.29 |
| 13 | Darrell Luter Jr. | USA | JR | CB | 7 | 4 | 5 | 9 | 1.29 |
| 13 | Bryquice Brown | Georgia St | SO | CB | 7 | 2 | 7 | 9 | 1.29 |
| 16 | Charles Amankwaa | Akron | JR | DB | 8 | 2 | 8 | 10 | 1.25 |
| 16 | Tyreek Chappell | Texas A&M | FR | DB | 8 | 1 | 9 | 10 | 1.25 |
| 16 | Jaylon Monroe | Tulane | SR | CB | 8 | 0 | 10 | 10 | 1.25 |
| 19 | Steven Jones Jr. | App St | SR | DB | 9 | 5 | 6 | 11 | 1.22 |
| 20 | Mario Goodrich | Clemson | SR | CB | 7 | 0 | 8 | 8 | 1.14 |
| 21 | Montaric Brown | Arkansas | SR | DB | 8 | 4 | 5 | 9 | 1.13 |
| 21 | Antavious Lane | Georgia St | SO | S | 8 | 4 | 5 | 9 | 1.13 |
| 21 | Tre Bugg III | Air Force | SR | DB | 8 | 2 | 7 | 9 | 1.13 |
| 21 | Lu-Magia Hearns III | California | FR | CB | 8 | 1 | 8 | 9 | 1.13 |
| 21 | Jakorian Bennett | Maryland | SR | DB | 8 | 1 | 8 | 9 | 1.13 |
| 21 | Natrone Brooks | USM | JR | DB | 8 | 1 | 8 | 9 | 1.13 |
| 21 | Kyu Blu Kelly | Stanford | JR | CB | 8 | 1 | 8 | 9 | 1.13 |
| 21 | Robert Longerbeam | Rutgers | FR | DB | 8 | 0 | 9 | 9 | 1.13 |
| 29 | Dadrion Taylor-Demerson | Texas Tech | JR | DB | 9 | 3 | 7 | 10 | 1.11 |
| 29 | Russ Yeast | Kansas St | SR | DB | 9 | 2 | 8 | 10 | 1.11 |
| 29 | Cam Taylor-Britt | Nebraska | JR | CB | 9 | 1 | 9 | 10 | 1.11 |
| 29 | Jaylin Williams | Indiana | SR | DB | 9 | 0 | 10 | 10 | 1.11 |
| 33 | Dane Belton | Iowa | JR | DB | 10 | 5 | 6 | 11 | 1.10 |
| 33 | Clark Phillips III | Utah | FR | CB | 10 | 1 | 10 | 11 | 1.10 |
| 35 | Erick Hallett II | Pittsburgh | JR | DB | 9 | 3 | 6 | 9 | 1.00 |
| 35 | Caesar Williams | Wisconsin | SR | CB | 9 | 3 | 6 | 9 | 1.00 |
| 35 | Denzel Burke | Ohio State | FR | CB | 9 | 1 | 8 | 9 | 1.00 |
| 35 | Tarheeb Still | Maryland | SO | DB | 9 | 0 | 9 | 9 | 1.00 |
| 35 | Evan Williams | Fresno St | JR | DB | 8 | 3 | 5 | 8 | 1.00 |
| 35 | Kenneth Harris | Ark St | FR | CB | 8 | 2 | 6 | 8 | 1.00 |
| 35 | Ja'Quan McMillian | ECU | SO | CB | 8 | 2 | 6 | 8 | 1.00 |
| 35 | Steven Gilmore | Marshall | JR | DB | 8 | 2 | 6 | 8 | 1.00 |
| 35 | Joe Joe Headen | ODU | SR | S | 8 | 2 | 6 | 8 | 1.00 |
| 35 | Travon Fuller | Tulsa | SR | CB | 8 | 2 | 6 | 8 | 1.00 |
| 35 | Starling Thomas V | UAB | JR | CB | 8 | 1 | 7 | 8 | 1.00 |
| 35 | Davonte Brown | UCF | SO | DB | 8 | 1 | 7 | 8 | 1.00 |
| 35 | Malik Fleming | ECU | SO | CB | 8 | 1 | 7 | 8 | 1.00 |
| 35 | Zyon Gilbert | FAU | SR | CB | 8 | 1 | 7 | 8 | 1.00 |
| 35 | Quindell Johnson | Memphis | JR | DB | 8 | 1 | 7 | 8 | 1.00 |
| 35 | Micah Abraham | Marshall | SO | DB | 8 | 0 | 8 | 8 | 1.00 |
| 35 | Romain Mungin | FAU | SO | CB | 7 | 2 | 5 | 7 | 1.00 |
| 35 | Cam Smith | S Carolina | SO | DB | 7 | 2 | 5 | 7 | 1.00 |
| 35 | Theo Jackson | Tennessee | SR | DB | 7 | 1 | 6 | 7 | 1.00 |
| 35 | Teldrick Ross | MTSU | SO | S | 7 | 0 | 7 | 7 | 1.00 |
| 35 | Garrett Williams | Syracuse | FR | DB | 7 | 0 | 7 | 7 | 1.00 |
| 35 | Nick Grant | Virginia | SR | CB | 7 | 0 | 7 | 7 | 1.00 |
| 35 | Omarion Cooper | FSU | FR | DB | 6 | 2 | 4 | 6 | 1.00 |
| 35 | Nazeeh Johnson | Marshall | SR | S | 6 | 2 | 4 | 6 | 1.00 |
| 35 | Josh Ferguson | NMSU | FR | LB | 1 | 0 | 1 | 1 | 1.00 |
| 35 | Donavan King | NMSU | JR | DL | 1 | 0 | 1 | 1 | 1.00 |
| 61 | Jarrick Bernard-Converse | Okla St | SR | CB | 10 | 0 | 9 | 9 | 0.90 |
| 62 | Coby Bryant | Cincinnati | SR | CB | 9 | 3 | 5 | 8 | 0.89 |
| 62 | Patrick McMorris | SDSU | JR | S | 9 | 3 | 5 | 8 | 0.89 |
| 62 | Eric Garror | La-Lafytte | JR | CB | 9 | 2 | 6 | 8 | 0.89 |
| 62 | Damarion Williams | Houston | SR | CB | 9 | 1 | 7 | 8 | 0.89 |
| 62 | Tony Grimes | N Carolina | SO | DB | 9 | 0 | 8 | 8 | 0.89 |
| 62 | Tayler Hawkins | SDSU | SR | CB | 9 | 0 | 8 | 8 | 0.89 |
| 68 | Grayson Cash | UAB | JR | S | 8 | 3 | 4 | 7 | 0.88 |
| 68 | TieNeal Martin | Tulsa | SR | S | 8 | 3 | 4 | 7 | 0.88 |
| 68 | J.T. Wahee | Ball State | SR | S | 8 | 2 | 5 | 7 | 0.88 |
| 68 | Jordan Anderson | BGSU | JR | S | 8 | 2 | 5 | 7 | 0.88 |
| 68 | Jacobi Francis | Memphis | SR | DB | 8 | 2 | 5 | 7 | 0.88 |
| 68 | Roman Parodie | Ohio | FR | CB | 8 | 2 | 5 | 7 | 0.88 |
| 68 | R'Tarriun Johnson | ODU | JR | S | 8 | 2 | 5 | 7 | 0.88 |
| 68 | Gabe Taylor | Rice | FR | DB | 8 | 2 | 5 | 7 | 0.88 |
| 68 | Dallas Branch | SDSU | JR | CB | 8 | 2 | 5 | 7 | 0.88 |
| 68 | Darian Chestnut | Syracuse | FR | DB | 8 | 2 | 5 | 7 | 0.88 |
| 68 | Jordan Helm | FAU | SR | S | 8 | 1 | 6 | 7 | 0.88 |
| 68 | Montre Miller | Kent State | JR | CB | 8 | 1 | 6 | 7 | 0.88 |
| 68 | Reed Blankenship | MTSU | SR | S | 8 | 1 | 6 | 7 | 0.88 |
| 68 | Armani Chatman | Va Tech | SO | DB | 8 | 1 | 6 | 7 | 0.88 |
| 68 | D'Jordan Strong | Coast Car | SR | CB | 8 | 0 | 7 | 7 | 0.88 |
| 68 | Anthony Wilson | Ga South | SO | S | 8 | 0 | 7 | 7 | 0.88 |
| 68 | Greedy Vance | Louisville | FR | DB | 8 | 0 | 7 | 7 | 0.88 |
| 68 | Jordan Dunbar | Rice | FR | CB | 8 | 0 | 7 | 7 | 0.88 |
| 68 | Bobby Brown, II | SJSU | SR | DB | 8 | 0 | 7 | 7 | 0.88 |
| 68 | Kordell Rodgers | Texas St | JR | CB | 8 | 0 | 7 | 7 | 0.88 |
| 68 | Tyon Davis | Tulsa | SR | CB | 8 | 0 | 7 | 7 | 0.88 |
| 68 | Dorian Jackson | W Mich | JR | CB | 8 | 0 | 7 | 7 | 0.88 |
| 90 | Nate Rutchena | California | FR | ILB | 7 | 3 | 3 | 6 | 0.86 |
| 90 | Joey Blount | Virginia | SR | FS | 7 | 3 | 3 | 6 | 0.86 |
| 90 | Quavian White | Georgia St | SR | CB | 7 | 1 | 5 | 6 | 0.86 |
| 90 | Kenyon Reed | SJSU | SO | CB | 7 | 1 | 5 | 6 | 0.86 |
| 90 | Jahari Rogers | SMU | FR | CB | 7 | 0 | 6 | 6 | 0.86 |
| 90 | Allan George | Vanderbilt | SR | CB | 7 | 0 | 6 | 6 | 0.86 |
| 96 | Tyson Williams | Nevada | SR | DB | 6 | 3 | 2 | 5 | 0.83 |
| 96 | John Saunders Jr. | Miami (Oh) | FR | DB | 6 | 1 | 4 | 5 | 0.83 |
| 96 | De'Vante Cross | Virginia | SR | FS | 6 | 1 | 4 | 5 | 0.83 |
| 99 | Devin Lloyd | Utah | JR | LB | 10 | 3 | 5 | 8 | 0.80 |
| 99 | Daxton Hill | Michigan | JR | DB | 10 | 2 | 6 | 8 | 0.80 |
Note: To qualify, player must have played in 75% of his team's games.