2021 National Leaders Passes Defended - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Ja'Quan McMillian | ECU | SO | CB | 4 | 3 | 9 | 12 | 3.00 |
| 2 | Greg Rubin | Memphis | FR | DB | 4 | 0 | 10 | 10 | 2.50 |
| 3 | A.J. Hampton, Jr. | N'western | JR | DB | 3 | 0 | 6 | 6 | 2.00 |
| 4 | Jakorian Bennett | Maryland | SR | DB | 4 | 2 | 5 | 7 | 1.75 |
| 4 | Max Melton | Rutgers | FR | DB | 4 | 2 | 5 | 7 | 1.75 |
| 4 | Rishard Dames | FIU | JR | DB | 4 | 1 | 6 | 7 | 1.75 |
| 4 | Malik Shorts | USM | SO | DB | 4 | 1 | 6 | 7 | 1.75 |
| 4 | Cam Smith | S Carolina | SO | DB | 4 | 1 | 6 | 7 | 1.75 |
| 9 | Darrell Luter Jr. | USA | JR | CB | 3 | 0 | 5 | 5 | 1.67 |
| 9 | Cameron Brown | Ohio State | JR | CB | 3 | 0 | 5 | 5 | 1.67 |
| 11 | Cortez Davis | Hawai'i | SR | DB | 5 | 0 | 8 | 8 | 1.60 |
| 12 | Kitan Oladapo | Oregon St | SO | DB | 4 | 1 | 5 | 6 | 1.50 |
| 12 | Bobby Brown, II | SJSU | SR | DB | 4 | 0 | 6 | 6 | 1.50 |
| 14 | Arquon Bush | Cincinnati | JR | CB | 5 | 2 | 5 | 7 | 1.40 |
| 14 | Dorian Jackson | W Mich | JR | CB | 5 | 2 | 5 | 7 | 1.40 |
| 14 | Micah Abraham | Marshall | SO | DB | 5 | 1 | 6 | 7 | 1.40 |
| 17 | Deontai Williams | Nebraska | SR | S | 3 | 2 | 2 | 4 | 1.33 |
| 17 | Collin Gamble | California | SO | CB | 3 | 0 | 4 | 4 | 1.33 |
| 19 | Verone McKinley III | Oregon | SO | S | 4 | 3 | 2 | 5 | 1.25 |
| 19 | Ji'Ayir Brown | Penn State | SR | S | 4 | 3 | 2 | 5 | 1.25 |
| 19 | Tavian Combs | New Mexico | SO | S | 4 | 2 | 3 | 5 | 1.25 |
| 19 | Josh Newton | La-Monroe | SO | CB | 4 | 2 | 3 | 5 | 1.25 |
| 19 | Andrew Booth Jr. | Clemson | JR | CB | 4 | 2 | 3 | 5 | 1.25 |
| 19 | Tayler Hawkins | SDSU | SR | CB | 4 | 2 | 3 | 5 | 1.25 |
| 19 | Devin Taylor | BGSU | SR | CB | 4 | 1 | 4 | 5 | 1.25 |
| 19 | Malcolm Rodriguez | Okla St | SR | LB | 4 | 1 | 4 | 5 | 1.25 |
| 19 | Lummie Young IV | Duke | SR | S | 4 | 1 | 4 | 5 | 1.25 |
| 19 | Donte Martin | New Mexico | JR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 19 | DaMarcus Fields | Texas Tech | SR | DB | 4 | 0 | 5 | 5 | 1.25 |
| 19 | Rayshad Williams | Texas Tech | JR | DB | 4 | 0 | 5 | 5 | 1.25 |
| 19 | Rejzohn Wright | Oregon St | JR | DB | 4 | 0 | 5 | 5 | 1.25 |
| 19 | Kessawn Abraham | Rutgers | JR | DB | 4 | 0 | 5 | 5 | 1.25 |
| 33 | Elvis Hines | Kent State | SR | CB | 5 | 3 | 3 | 6 | 1.20 |
| 33 | Samuel Womack | Toledo | SR | CB | 5 | 2 | 4 | 6 | 1.20 |
| 33 | Teldrick Ross | MTSU | SO | S | 5 | 1 | 5 | 6 | 1.20 |
| 33 | Davonte Brown | UCF | SO | DB | 5 | 0 | 6 | 6 | 1.20 |
| 33 | Theo Jackson | Tennessee | SR | DB | 5 | 0 | 6 | 6 | 1.20 |
| 33 | C.J. Coldon | Wyoming | JR | CB | 5 | 0 | 6 | 6 | 1.20 |
| 33 | Coby Bryant | Cincinnati | SR | CB | 5 | 0 | 6 | 6 | 1.20 |
| 33 | Jordan Gandy | N Illinois | SO | CB | 5 | 0 | 6 | 6 | 1.20 |
| 41 | Montre Miller | Kent State | JR | CB | 5 | 3 | 2 | 5 | 1.00 |
| 41 | Bryan Cook | Cincinnati | SR | S | 5 | 2 | 3 | 5 | 1.00 |
| 41 | Levelle Bailey | Fresno St | JR | LB | 5 | 1 | 4 | 5 | 1.00 |
| 41 | Elijah Gates | Fresno St | SR | DB | 5 | 1 | 4 | 5 | 1.00 |
| 41 | Khoury Bethley | Hawai'i | SR | DB | 5 | 1 | 4 | 5 | 1.00 |
| 41 | Travon Fuller | Tulsa | SR | CB | 5 | 1 | 4 | 5 | 1.00 |
| 41 | Darius Rush | S Carolina | JR | DB | 5 | 1 | 4 | 5 | 1.00 |
| 41 | Patrick McMorris | SDSU | JR | S | 5 | 1 | 4 | 5 | 1.00 |
| 41 | Tre Bugg III | Air Force | SR | DB | 5 | 0 | 5 | 5 | 1.00 |
| 41 | Mekhi Garner | La-Lafytte | SO | CB | 5 | 0 | 5 | 5 | 1.00 |
| 41 | JT Woods | Baylor | SR | S | 4 | 3 | 1 | 4 | 1.00 |
| 41 | Jermaine Waller | Va Tech | JR | DB | 4 | 3 | 1 | 4 | 1.00 |
| 41 | Josh DeBerry | BC | JR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 41 | Russ Yeast | Kansas St | SR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 41 | Leon O'Neal Jr. | Texas A&M | SR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 41 | Anthony Johnson | Virginia | JR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 41 | Cameron Lockridge | Hawai'i | JR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Nehemiah Shelton | SJSU | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Nic Jones | Ball State | JR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Clark Phillips III | Utah | FR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Jerrick Reed II | New Mexico | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Tyreque Jones | Boise St | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Warren Saba | ECU | SR | SAF | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Jalen Green | Miss St | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Trey Baldwin | La Tech | SR | LB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Jarius Reimonenq | Ark St | SO | S | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Leon Jones | Ark St | SO | CB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Darian Chestnut | Syracuse | FR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Jayden Peevy | Texas A&M | SR | DL | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Zyon Gilbert | FAU | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Bryan Massey | SMU | SO | S | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Alex Austin | Oregon St | FR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Leonard Johnson | Duke | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Cameron Martinez | Ohio State | FR | SAF | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Angelo Grose | Mich St | SO | S | 4 | 1 | 3 | 4 | 1.00 |
| 41 | Davon Ferguson | BGSU | SR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Daevion Davis | Vanderbilt | JR | DL | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Taylon Doss | Ark St | FR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | D.C. Williams | Texas St | SR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Marcus Jones | Houston | SR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Rodney Owens | Memphis | SR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Quindell Johnson | Memphis | JR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Dishon McNary | CMU | JR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Brad Hawkins | Michigan | SR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Jalen Graham | Purdue | JR | LB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Denzel Burke | Ohio State | FR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 41 | Matt Hankins | Iowa | SR | DB | 3 | 2 | 1 | 3 | 1.00 |
| 41 | Jack Jones | Ariz St | SR | DB | 3 | 1 | 2 | 3 | 1.00 |
| 41 | Caelen Carson | Wk Forest | FR | DB | 3 | 1 | 2 | 3 | 1.00 |
| 41 | Mekhi Blackmon | Colorado | JR | CB | 3 | 1 | 2 | 3 | 1.00 |
| 41 | Kyu Blu Kelly | Stanford | JR | CB | 3 | 1 | 2 | 3 | 1.00 |
| 41 | Luke Reimer | Nebraska | SO | ILB | 3 | 1 | 2 | 3 | 1.00 |
| 41 | Chris Steele | USC | JR | CB | 3 | 1 | 2 | 3 | 1.00 |
| 41 | Kerby Joseph | Illinois | JR | DB | 3 | 1 | 2 | 3 | 1.00 |
| 41 | Quentin Lake | UCLA | SR | DB | 3 | 0 | 3 | 3 | 1.00 |
| 41 | Nate Landman | Colorado | SR | ILB | 3 | 0 | 3 | 3 | 1.00 |
| 41 | Kenny Logan Jr. | Kansas | JR | S | 3 | 0 | 3 | 3 | 1.00 |
| 41 | Garrett Williams | Syracuse | FR | DB | 3 | 0 | 3 | 3 | 1.00 |
| 41 | Brandon Bouyer-Randle | Texas Tech | SR | LB | 3 | 0 | 3 | 3 | 1.00 |
| 41 | Trent McDuffie | Washington | SO | DB | 3 | 0 | 3 | 3 | 1.00 |
Note: To qualify, player must have played in 75% of his team's games.