2021 National Leaders Long All Purpose Plays - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Jameson Williams | Alabama | JR | WR | 10 | 14 | 9 | 8 | 6 | 5 | 4 | 2 |
| 2 | Matt Landers | Toledo | JR | WR | 11 | 5 | 4 | 3 | 3 | 3 | 3 | 1 |
| 3 | Treylon Burks | Arkansas | JR | WR | 9 | 7 | 5 | 3 | 2 | 2 | 2 | 1 |
| 3 | LaMareon James | ODU | FR | CB | 12 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
| 3 | Marcus Jones | Houston | SR | CB | 12 | 8 | 8 | 3 | 3 | 3 | 2 | 2 |
| 3 | Alan Lamar | Ark St | SR | RB | 11 | 10 | 3 | 3 | 2 | 2 | 2 | 2 |
| 3 | Jayden Reed | Mich St | JR | WR | 10 | 13 | 7 | 4 | 4 | 3 | 2 | 0 |
| 3 | Jack Sorenson | Miami (Oh) | SR | WR | 12 | 11 | 6 | 5 | 2 | 2 | 2 | 0 |
| 3 | Sean Tyler | W Mich | SO | RB | 11 | 7 | 4 | 4 | 4 | 3 | 2 | 2 |
| 3 | Jalen Virgil | App St | SR | WR | 10 | 10 | 6 | 3 | 3 | 2 | 2 | 2 |
| 3 | Winston Wright Jr. | WVU | JR | WR | 10 | 5 | 4 | 2 | 2 | 2 | 2 | 2 |
| 12 | Israel Abanikanda | Pittsburgh | SO | RB | 10 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Kris Abrams-Draine | Missouri | SO | DB | 10 | 3 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Carlinos Acie | Navy | SR | SB | 9 | 2 | 2 | 2 | 2 | 1 | 1 | 1 |
| 12 | Tyrell Ajian | Kentucky | SR | DB | 11 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Rasheen Ali | Marshall | FR | RB | 12 | 5 | 5 | 3 | 1 | 1 | 1 | 1 |
| 12 | Kazmeir Allen | UCLA | JR | RB | 10 | 8 | 6 | 4 | 3 | 2 | 1 | 1 |
| 12 | Calvin Austin III | Memphis | SR | WR | 11 | 9 | 7 | 6 | 4 | 2 | 1 | 1 |
| 12 | Brian Battie | S Florida | SO | RB | 8 | 3 | 3 | 1 | 1 | 1 | 1 | 1 |
| 12 | Jaheim Bell | S Carolina | SO | TE | 10 | 4 | 4 | 3 | 3 | 1 | 1 | 0 |
| 12 | Kivon Bennett | Ark St | JR | DL | 11 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Ulysses Bentley IV | SMU | SO | RB | 9 | 4 | 3 | 3 | 2 | 2 | 1 | 0 |
| 12 | Zavier Betts | Nebraska | FR | WR | 7 | 3 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Reed Blankenship | MTSU | SR | S | 13 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Zion Bowens | Hawai'i | SR | WR | 10 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Brock Bowers | Georgia | FR | TE | 9 | 4 | 2 | 2 | 2 | 2 | 1 | 0 |
| 12 | Stephan Bracey | Wisconsin | SO | WR | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Brian Brewton | UConn | FR | RB | 9 | 3 | 2 | 1 | 1 | 1 | 1 | 1 |
| 12 | Chase Brown | Illinois | SO | RB | 9 | 4 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Ji'Ayir Brown | Penn State | SR | S | 8 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | LD Brown | Okla St | SR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Leddie Brown | WVU | SR | RB | 9 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 12 | Jalon Calhoun | Duke | JR | WR | 10 | 3 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | David Carter Jr. | EMU | FR | DB | 13 | 2 | 2 | 1 | 1 | 1 | 1 | 1 |
| 12 | Grayson Cash | UAB | JR | S | 11 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Dante Cephas | Kent State | SO | WR | 13 | 10 | 8 | 3 | 1 | 1 | 1 | 0 |
| 12 | Tyrese Chambers | FIU | SO | WR | 12 | 15 | 10 | 6 | 5 | 2 | 1 | 1 |
| 12 | Trevon Clark | California | SR | WR | 11 | 7 | 3 | 3 | 2 | 1 | 1 | 0 |
| 12 | Trey Cobb | App St | SR | ILB | 12 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Stefan Cobbs | Boise St | JR | WR | 6 | 5 | 2 | 2 | 2 | 1 | 1 | 0 |
| 12 | Tyleek Collins | UNLV | SR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Sam Crawford Jr. | Tulsa | SR | WR | 5 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Jalen Cropper | Fresno St | JR | WR | 11 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Haaziq Daniels | Air Force | JR | QB | 10 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Derius Davis | TCU | SR | WR | 9 | 8 | 6 | 2 | 2 | 2 | 1 | 1 |
| 12 | Kevin Davis | Miami (Oh) | FR | RB | 12 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 12 | Will Derrick | La-Monroe | JR | WR | 10 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Jahan Dotson | Penn State | SR | WR | 8 | 10 | 5 | 2 | 1 | 1 | 1 | 0 |
| 12 | Trestan Ebner | Baylor | SR | RB | 9 | 10 | 6 | 4 | 2 | 1 | 1 | 1 |
| 12 | Emeka Egbuka | Ohio State | FR | WR | 9 | 7 | 4 | 2 | 2 | 1 | 1 | 0 |
| 12 | Tiyon Evans | Tennessee | JR | RB | 5 | 3 | 3 | 1 | 1 | 1 | 1 | 1 |
| 12 | Johnny Ford | FAU | SO | RB | 11 | 9 | 2 | 2 | 2 | 1 | 1 | 0 |
| 12 | Jeff Foreman | Ark St | SO | WR | 11 | 3 | 3 | 2 | 2 | 1 | 1 | 0 |
| 12 | Jahmyr Gibbs | Ga Tech | FR | RB | 8 | 9 | 6 | 5 | 4 | 3 | 1 | 1 |
| 12 | Isaac Guerendo | Wisconsin | JR | RB | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Breece Hall | Iowa State | JR | RB | 8 | 9 | 6 | 4 | 3 | 3 | 1 | 0 |
| 12 | Justin Hall | Ball State | SR | WR | 11 | 10 | 4 | 2 | 2 | 2 | 1 | 1 |
| 12 | Camron Harrell | USM | JR | DB | 11 | 6 | 2 | 2 | 2 | 1 | 1 | 1 |
| 12 | Tyler Harrell | Louisville | SO | WR | 8 | 7 | 2 | 2 | 1 | 1 | 1 | 1 |
| 12 | Cam'Ron Harris | Miami (Fl) | JR | RB | 4 | 3 | 3 | 3 | 1 | 1 | 1 | 0 |
| 12 | Jayden Harrison | Marshall | SO | WR | 12 | 4 | 2 | 1 | 1 | 1 | 1 | 1 |
| 12 | Maquel Haywood | Navy | FR | SB | 6 | 3 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Joe Joe Headen | ODU | SR | S | 12 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Ta'Zhawn Henry | Houston | JR | RB | 12 | 3 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Chris Hilton Jr. | LSU | FR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Alex Hogan | Houston | JR | CB | 13 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Ahmari Huggins-Bruce | Louisville | FR | WR | 7 | 2 | 2 | 1 | 1 | 1 | 1 | 1 |
| 12 | Evan Hull | N'western | SO | RB | 9 | 3 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Dae Dae Hunter | Hawai'i | SO | RB | 10 | 5 | 3 | 3 | 2 | 2 | 1 | 0 |
| 12 | Jarquez Hunter | Auburn | FR | RB | 8 | 4 | 2 | 1 | 1 | 1 | 1 | 1 |
| 12 | Cornelius Johnson | Michigan | JR | WR | 10 | 4 | 2 | 2 | 1 | 1 | 1 | 0 |
| 12 | Montrell Johnson | La-Lafytte | FR | RB | 14 | 3 | 2 | 1 | 1 | 1 | 1 | 1 |
| 12 | Charlie Jones | Iowa | SR | WR | 12 | 10 | 4 | 2 | 2 | 2 | 1 | 1 |
| 12 | Jack Jones | Ariz St | SR | DB | 9 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Velus Jones Jr. | Tennessee | SR | WR | 8 | 9 | 4 | 2 | 1 | 1 | 1 | 1 |
| 12 | Jawhar Jordan | Louisville | FR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Zonovan Knight | NC State | SO | RB | 10 | 4 | 3 | 1 | 1 | 1 | 1 | 1 |
| 12 | KeAndre Lambert-Smith | Penn State | SO | WR | 8 | 4 | 3 | 2 | 1 | 1 | 1 | 0 |
| 12 | Tyric LeBeauf | Boise St | JR | CB | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Travis Levy | BC | SR | RB | 9 | 3 | 2 | 2 | 2 | 1 | 1 | 1 |
| 12 | Brandon Lewis | Air Force | SR | WR | 11 | 9 | 6 | 4 | 3 | 1 | 1 | 1 |
| 12 | Isaiah Likely | Coast Car | SR | TE | 13 | 6 | 3 | 2 | 2 | 1 | 1 | 1 |
| 12 | Kenny Logan Jr. | Kansas | JR | S | 9 | 3 | 2 | 2 | 2 | 1 | 1 | 0 |
| 12 | Marion Lukes | CMU | FR | RB | 13 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Devin Maddox | Toledo | SO | WR | 12 | 4 | 2 | 2 | 2 | 1 | 1 | 0 |
| 12 | Bryan Massey | SMU | SO | S | 10 | 7 | 4 | 2 | 1 | 1 | 1 | 1 |
| 12 | Michael Mathison | Akron | SO | WR | 10 | 7 | 2 | 2 | 1 | 1 | 1 | 1 |
| 12 | D.J. Matthews Jr. | Indiana | SR | WR | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Sincere McCormick | UTSA | JR | RB | 13 | 4 | 4 | 3 | 3 | 2 | 1 | 0 |
| 12 | Keaton Mitchell | ECU | FR | RB | 10 | 9 | 7 | 6 | 5 | 2 | 1 | 0 |
| 12 | Leon O'Neal Jr. | Texas A&M | SR | DB | 9 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Lincoln Pare | Ark St | FR | RB | 11 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Nathan Parodi | Arkansas | JR | DB | 9 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Nathaniel Peat | Stanford | JR | RB | 9 | 6 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Kyle Philips | UCLA | JR | WR | 9 | 6 | 6 | 3 | 2 | 2 | 1 | 0 |
| 12 | Kalil Pimpleton | CMU | JR | WR | 13 | 11 | 7 | 4 | 3 | 3 | 1 | 1 |
| 12 | TJ Pledger | Utah | JR | RB | 9 | 5 | 3 | 2 | 1 | 1 | 1 | 1 |
| 12 | Nehemiah Pritchett | Auburn | JR | CB | 8 | 3 | 2 | 2 | 2 | 2 | 1 | 0 |
| 12 | Clint Ratkovich | N Illinois | SR | RB | 13 | 2 | 2 | 2 | 1 | 1 | 1 | 1 |
| 12 | Traveon Redd | Wk Forest | SR | DB | 11 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |