2021 National Leaders Passes Defended - Games in August/September Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Ja'Quan McMillian | ECU | SO | CB | 4 | 3 | 9 | 12 | 3.00 |
| 2 | Greg Rubin | Memphis | FR | DB | 4 | 0 | 10 | 10 | 2.50 |
| 3 | Caelen Carson | Wk Forest | FR | DB | 4 | 2 | 6 | 8 | 2.00 |
| 3 | Jakorian Bennett | Maryland | SR | DB | 4 | 2 | 6 | 8 | 2.00 |
| 5 | Arquon Bush | Cincinnati | JR | CB | 3 | 2 | 5 | 7 | 2.33 |
| 5 | Corvan Taylor | Air Force | SR | SS | 4 | 3 | 4 | 7 | 1.75 |
| 5 | Rishard Dames | FIU | JR | DB | 4 | 1 | 6 | 7 | 1.75 |
| 5 | Malik Shorts | USM | SO | DB | 4 | 1 | 6 | 7 | 1.75 |
| 5 | Rejzohn Wright | Oregon St | JR | DB | 4 | 1 | 6 | 7 | 1.75 |
| 5 | Devon Witherspoon | Illinois | SO | DB | 4 | 0 | 7 | 7 | 1.75 |
| 5 | A.J. Hampton, Jr. | N'western | JR | DB | 4 | 0 | 7 | 7 | 1.75 |
| 5 | Cortez Davis | Hawai'i | SR | DB | 5 | 0 | 7 | 7 | 1.40 |
| 13 | Max Melton | Rutgers | FR | DB | 3 | 2 | 4 | 6 | 2.00 |
| 13 | Verone McKinley III | Oregon | SO | S | 4 | 4 | 2 | 6 | 1.50 |
| 13 | Elvis Hines | Kent State | SR | CB | 4 | 3 | 3 | 6 | 1.50 |
| 13 | Kyu Blu Kelly | Stanford | JR | CB | 4 | 2 | 4 | 6 | 1.50 |
| 13 | Denzel Burke | Ohio State | FR | CB | 4 | 0 | 6 | 6 | 1.50 |
| 13 | Yusuf Corker | Kentucky | SR | DB | 4 | 0 | 6 | 6 | 1.50 |
| 13 | Nick Grant | Virginia | SR | CB | 4 | 0 | 6 | 6 | 1.50 |
| 13 | Jordan Gandy | N Illinois | SO | CB | 4 | 0 | 6 | 6 | 1.50 |
| 21 | Syrus Dumas | NMSU | SO | DB | 2 | 2 | 3 | 5 | 2.50 |
| 21 | Cameron Brown | Ohio State | JR | CB | 2 | 0 | 5 | 5 | 2.50 |
| 21 | Darrell Luter Jr. | USA | JR | CB | 3 | 0 | 5 | 5 | 1.67 |
| 21 | Jermaine Waller | Va Tech | JR | DB | 4 | 3 | 2 | 5 | 1.25 |
| 21 | Justin Rice | Utah State | SR | ILB | 4 | 3 | 2 | 5 | 1.25 |
| 21 | Montre Miller | Kent State | JR | CB | 4 | 3 | 2 | 5 | 1.25 |
| 21 | Kyle Hamilton | Notre Dame | JR | S | 4 | 3 | 2 | 5 | 1.25 |
| 21 | Kei'Trel Clark | Louisville | SO | DB | 4 | 3 | 2 | 5 | 1.25 |
| 21 | Tavian Combs | New Mexico | SO | S | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Seyi Oladipo | Boise St | FR | S | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Tyreque Jones | Boise St | SR | S | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Jalen Catalon | Arkansas | SO | DB | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Ji'Ayir Brown | Penn State | SR | S | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Riley Moss | Iowa | SR | DB | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Nick Cross | Maryland | JR | DB | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Marquel Broughton | Army | JR | DB | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Cam Hart | Notre Dame | SO | CB | 4 | 2 | 3 | 5 | 1.25 |
| 21 | Travon Fuller | Tulsa | SR | CB | 4 | 1 | 4 | 5 | 1.25 |
| 21 | Devin Taylor | BGSU | SR | CB | 4 | 1 | 4 | 5 | 1.25 |
| 21 | Angelo Grose | Mich St | SO | S | 4 | 1 | 4 | 5 | 1.25 |
| 21 | Lewis Cine | Georgia | JR | DB | 4 | 1 | 4 | 5 | 1.25 |
| 21 | Dorian Jackson | W Mich | JR | CB | 4 | 1 | 4 | 5 | 1.25 |
| 21 | Teldrick Ross | MTSU | SO | S | 4 | 1 | 4 | 5 | 1.25 |
| 21 | Lummie Young IV | Duke | SR | S | 4 | 1 | 4 | 5 | 1.25 |
| 21 | Donte Martin | New Mexico | JR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 21 | Theo Jackson | Tennessee | SR | DB | 4 | 0 | 5 | 5 | 1.25 |
| 21 | Collin Gamble | California | SO | CB | 4 | 0 | 5 | 5 | 1.25 |
| 21 | C.J. Coldon | Wyoming | JR | CB | 4 | 0 | 5 | 5 | 1.25 |
| 21 | Kitan Oladapo | Oregon St | SO | DB | 4 | 0 | 5 | 5 | 1.25 |
| 21 | Levelle Bailey | Fresno St | JR | LB | 5 | 1 | 4 | 5 | 1.00 |
| 21 | Cameron Lockridge | Hawai'i | JR | DB | 5 | 1 | 4 | 5 | 1.00 |
| 52 | Faion Hicks | Wisconsin | SR | CB | 2 | 0 | 4 | 4 | 2.00 |
| 52 | Tayler Hawkins | SDSU | SR | CB | 3 | 2 | 2 | 4 | 1.33 |
| 52 | Dyllon Lester | UCF | JR | DB | 3 | 1 | 3 | 4 | 1.33 |
| 52 | Kaiir Elam | Florida | JR | CB | 3 | 1 | 3 | 4 | 1.33 |
| 52 | Jimmy Wyrick | Stanford | FR | CB | 3 | 1 | 3 | 4 | 1.33 |
| 52 | Jordan Wright | Kentucky | SR | OLB | 3 | 0 | 4 | 4 | 1.33 |
| 52 | Jaylan Foster | S Carolina | SR | DB | 4 | 4 | 0 | 4 | 1.00 |
| 52 | Tyric LeBeauf | Boise St | JR | CB | 4 | 3 | 1 | 4 | 1.00 |
| 52 | Emmanuel Forbes | Miss St | SO | CB | 4 | 2 | 2 | 4 | 1.00 |
| 52 | Josh DeBerry | BC | JR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 52 | Leon O'Neal Jr. | Texas A&M | SR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 52 | Kyler Gordon | Washington | SO | DB | 4 | 2 | 2 | 4 | 1.00 |
| 52 | Myles Bell | UConn | SO | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Tanner Ingle | NC State | JR | SAF | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Nic Jones | Ball State | JR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Cameron Martinez | Ohio State | FR | SAF | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Jerrick Reed II | New Mexico | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Warren Saba | ECU | SR | SAF | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Jaylen McCollough | Tennessee | JR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Jacquez Jones | Kentucky | SR | ILB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Ethan Barr | Vanderbilt | SO | LB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Jalen Green | Miss St | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Trey Baldwin | La Tech | SR | LB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Jarius Reimonenq | Ark St | SO | S | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Leon Jones | Ark St | SO | CB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Darian Chestnut | Syracuse | FR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Micah Abraham | Marshall | SO | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Kelee Ringo | Georgia | FR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Jayden Peevy | Texas A&M | SR | DL | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Zyon Gilbert | FAU | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Kris Abrams-Draine | Missouri | SO | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Bryan Massey | SMU | SO | S | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Alex Austin | Oregon St | FR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Alton Julian | Oregon St | SO | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Patrick McMorris | SDSU | JR | S | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Travis Jay | FSU | FR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Jack Kiser | Notre Dame | SO | LB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Leonard Johnson | Duke | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 52 | Nehemiah Shelton | SJSU | SR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Bobby Brown, II | SJSU | SR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Davon Ferguson | BGSU | SR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Tony Grimes | N Carolina | SO | DB | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Kenny Logan Jr. | Kansas | JR | S | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Daevion Davis | Vanderbilt | JR | DL | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Taylon Doss | Ark St | FR | CB | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Noah Boykin | U Mass | SO | DB | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Josh Wallace | U Mass | SO | CB | 4 | 0 | 4 | 4 | 1.00 |
| 52 | D.C. Williams | Texas St | SR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 52 | Antonio Johnson | Texas A&M | SO | DB | 4 | 0 | 4 | 4 | 1.00 |