2022 Conference USA Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Trey Moore | UTSA | FR | OLB | 2 | 2.0 | 14 | 1.00 |
| 2 | Jaiden Cole | La Tech | SR | DB | 1 | 1.0 | 9 | 1.00 |
| 3 | Amir Siddiq | Charlotte | SR | DL | 1 | 1.0 | 8 | 1.00 |
| 4 | JaQues Evans | Western Ky | SO | LB | 1 | 1.0 | 7 | 1.00 |
| 4 | Derrick Smith | Western Ky | SR | LB | 1 | 1.0 | 7 | 1.00 |
| 4 | Jamal Ligon | UTSA | JR | ILB | 2 | 1.0 | 7 | 0.50 |
| 7 | Trumane Bell II | UTSA | SR | DL | 1 | 1.0 | 6 | 1.00 |
| 7 | Joe Evans | UTSA | JR | DL | 2 | 1.0 | 6 | 0.50 |
| 9 | Corey Mayfield Jr. | UTSA | SR | CB | 2 | 1.0 | 5 | 0.50 |
| 10 | Ikenna Enechukwu | Rice | JR | DE | 1 | 1.0 | 3 | 1.00 |
| 11 | Juwuan Jones | Western Ky | SR | DE | 1 | 1.0 | 1 | 1.00 |
| 11 | Michael Fairbanks II | UAB | JR | OLB | 1 | 0.5 | 1 | 0.50 |