2022 Conference USA Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Trey Moore | UTSA | FR | OLB | 2 | 2.0 | 14 | 1.00 |
| 1 | Jaiden Cole | La Tech | SR | DB | 1 | 1.0 | 9 | 1.00 |
| 1 | Amir Siddiq | Charlotte | SR | DL | 1 | 1.0 | 8 | 1.00 |
| 1 | JaQues Evans | Western Ky | SO | LB | 1 | 1.0 | 7 | 1.00 |
| 1 | Derrick Smith | Western Ky | SR | LB | 1 | 1.0 | 7 | 1.00 |
| 1 | Ikenna Enechukwu | Rice | JR | DE | 1 | 1.0 | 3 | 1.00 |
| 1 | Juwuan Jones | Western Ky | SR | DE | 1 | 1.0 | 1 | 1.00 |
| 8 | Jamal Ligon | UTSA | JR | ILB | 2 | 1.0 | 7 | 0.50 |
| 8 | Joe Evans | UTSA | JR | DL | 2 | 1.0 | 6 | 0.50 |
| 8 | Corey Mayfield Jr. | UTSA | SR | CB | 2 | 1.0 | 5 | 0.50 |
| 8 | Michael Fairbanks II | UAB | JR | OLB | 1 | 0.5 | 1 | 0.50 |
| 8 | Isaiah Forte | UAB | SR | DL | 1 | 0.5 | 0 | 0.50 |
| 8 | Aaron Key | Western Ky | FR | LB | 1 | 0.5 | 0 | 0.50 |
| 8 | Mike Allen | Western Ky | SR | DT | 1 | 0.5 | 0 | 0.50 |
Note: To qualify, player must have played in 75% of his team's games.