2022 Big 12 Conference Leaders Interceptions - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Colby Reeder | Iowa State | SR | LB | 4 | 2 | 66 | 0 | 0.50 |
| 2 | Daniel Green | Kansas St | SR | LB | 6 | 1 | 49 | 0 | 0.17 |
| 3 | Bud Clark | TCU | SO | S | 7 | 3 | 46 | 1 | 0.43 |
| 4 | Jahdae Barron | Texas | JR | DB | 7 | 1 | 44 | 1 | 0.14 |
| 5 | Malachi Ruffin | WVU | JR | DB | 6 | 2 | 43 | 1 | 0.33 |
| 6 | Rich Miller | Kansas | SR | LB | 8 | 1 | 37 | 0 | 0.13 |
| 7 | Reggie Pearson Jr. | Texas Tech | SR | DB | 6 | 2 | 36 | 0 | 0.33 |
| 8 | C.J. Coldon | Oklahoma | SR | DB | 5 | 3 | 32 | 0 | 0.60 |
| 8 | Josh Newton | TCU | JR | CB | 8 | 1 | 32 | 0 | 0.13 |
| 10 | Dee Winters | TCU | SR | LB | 8 | 1 | 29 | 1 | 0.13 |
| 11 | Jonah Laulu | Oklahoma | SR | DL | 6 | 1 | 26 | 0 | 0.17 |
| 11 | Kenny Logan Jr. | Kansas | SR | S | 8 | 1 | 26 | 0 | 0.13 |
| 13 | Devin Lemear | Baylor | FR | S | 7 | 1 | 21 | 0 | 0.14 |
| 14 | Tre'Vius Hodges-Tomlinson | TCU | SR | CB | 8 | 3 | 20 | 0 | 0.38 |
| 15 | Beau Freyler | Iowa State | SO | DB | 6 | 1 | 18 | 0 | 0.17 |
| 15 | AJ McCarty | Baylor | SO | CB | 7 | 1 | 18 | 1 | 0.14 |
| 15 | Jaylan Ford | Texas | JR | LB | 7 | 1 | 18 | 0 | 0.14 |
| 18 | Jason Taylor II | Okla St | SR | S | 5 | 2 | 16 | 0 | 0.40 |
| 18 | Trey Rucker | Okla St | SR | S | 1 | 1 | 16 | 0 | 1.00 |
| 20 | Mason Cobb | Okla St | JR | LB | 4 | 1 | 13 | 0 | 0.25 |
| 20 | Mello Dotson | Kansas | SO | CB | 8 | 1 | 13 | 0 | 0.13 |
| 22 | Marquis Waters | Texas Tech | SR | DB | 7 | 1 | 11 | 0 | 0.14 |
| 23 | Billy Bowman Jr. | Oklahoma | SO | DB | 5 | 2 | 8 | 0 | 0.40 |
| 23 | Kendal Daniels | Okla St | FR | S | 5 | 1 | 8 | 0 | 0.20 |
| 23 | Krew Jackson | Kansas St | FR | LB | 6 | 1 | 8 | 0 | 0.17 |
| 26 | Al Walcott | Baylor | SR | S | 7 | 1 | 4 | 0 | 0.14 |
| 27 | Mark Milton | Baylor | SR | CB | 6 | 1 | 2 | 0 | 0.17 |