2022 Big 12 Conference Leaders Opponent First Downs - Games vs. Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 9 | 78 | 105 | 11 | 194 | 21.6 |
| 1 | Baylor | 9 | 91 | 99 | 11 | 201 | 22.3 |
| 3 | TCU | 10 | 91 | 97 | 13 | 201 | 20.1 |
| 4 | Iowa State | 9 | 65 | 68 | 15 | 148 | 16.4 |
| 4 | Texas Tech | 9 | 88 | 96 | 15 | 199 | 22.1 |
| 4 | Kansas | 9 | 103 | 113 | 15 | 231 | 25.7 |
| 7 | Oklahoma | 9 | 105 | 121 | 16 | 242 | 26.9 |
| 8 | Kansas State | 10 | 76 | 109 | 18 | 203 | 20.3 |
| 8 | Texas | 9 | 67 | 109 | 18 | 194 | 21.6 |
| 8 | West Virginia | 9 | 87 | 110 | 18 | 215 | 23.9 |