2022 Big 12 Conference Leaders Opponent First Downs - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 3 | 14 | 21 | 3 | 38 | 12.7 |
| 2 | West Virginia | 3 | 15 | 25 | 4 | 44 | 14.7 |
| 2 | Kansas State | 4 | 29 | 29 | 4 | 62 | 15.5 |
| 2 | Texas | 4 | 28 | 50 | 4 | 82 | 20.5 |
| 5 | Oklahoma State | 4 | 30 | 43 | 5 | 78 | 19.5 |
| 6 | Texas Tech | 4 | 25 | 37 | 6 | 68 | 17.0 |
| 7 | Oklahoma | 4 | 34 | 52 | 7 | 93 | 23.3 |
| 8 | Baylor | 4 | 32 | 31 | 8 | 71 | 17.8 |
| 9 | Kansas | 4 | 40 | 42 | 10 | 92 | 23.0 |
| 10 | TCU | 5 | 41 | 65 | 11 | 117 | 23.4 |