2022 Big 12 Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 3 | 112 | 627 | 5.60 | 7 | 37.33 | 209.00 |
| 2 | Iowa State | 3 | 119 | 453 | 3.81 | 2 | 39.67 | 151.00 |
| 2 | Baylor | 3 | 119 | 507 | 4.26 | 9 | 39.67 | 169.00 |
| 4 | Texas Tech | 3 | 120 | 728 | 6.07 | 6 | 40.00 | 242.67 |
| 5 | Kansas | 3 | 130 | 801 | 6.16 | 12 | 43.33 | 267.00 |
| 6 | Texas | 4 | 131 | 617 | 4.71 | 4 | 32.75 | 154.25 |
| 7 | West Virginia | 4 | 139 | 482 | 3.47 | 9 | 34.75 | 120.50 |
| 8 | Oklahoma | 4 | 174 | 1101 | 6.33 | 14 | 43.50 | 275.25 |
| 9 | TCU | 5 | 180 | 831 | 4.62 | 12 | 36.00 | 166.20 |
| 10 | Kansas State | 5 | 206 | 1037 | 5.03 | 8 | 41.20 | 207.40 |