2022 Big 12 Conference Leaders Scoring Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 10 | 28 | 9 | 28 | 0 | 0 | 223 | 22.3 |
| 1 | Kansas State | 12 | 35 | 16 | 27 | 2 | 0 | 289 | 24.1 |
| 1 | Oklahoma State | 11 | 40 | 15 | 38 | 1 | 0 | 325 | 29.5 |
| 1 | TCU | 13 | 48 | 16 | 44 | 2 | 0 | 384 | 29.5 |
| 1 | Texas Tech | 11 | 41 | 18 | 37 | 1 | 0 | 339 | 30.8 |
| 1 | Oklahoma | 11 | 48 | 13 | 43 | 2 | 0 | 374 | 34.0 |
| 1 | West Virginia | 11 | 49 | 15 | 45 | 2 | 0 | 388 | 35.3 |
| 8 | Texas | 11 | 30 | 13 | 28 | 1 | 1 | 251 | 22.8 |
| 8 | Baylor | 9 | 35 | 10 | 32 | 1 | 1 | 276 | 30.7 |
| 8 | Kansas | 11 | 53 | 15 | 48 | 4 | 1 | 421 | 38.3 |