2022 Big 12 Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 10 | 1166 | 1708 | 603 | 2874 | 4.77 | 287.4 |
| 2 | Baylor | 9 | 1399 | 2174 | 621 | 3573 | 5.75 | 397.0 |
| 3 | West Virginia | 11 | 1713 | 3054 | 765 | 4767 | 6.23 | 433.4 |
| 4 | Texas Tech | 11 | 2057 | 2864 | 809 | 4921 | 6.08 | 447.4 |
| 5 | Kansas State | 12 | 1820 | 2826 | 813 | 4646 | 5.71 | 387.2 |
| 6 | Texas | 11 | 1403 | 2719 | 822 | 4122 | 5.01 | 374.7 |
| 7 | Oklahoma State | 11 | 2111 | 2777 | 832 | 4888 | 5.88 | 444.4 |
| 8 | Kansas | 11 | 2452 | 3013 | 853 | 5465 | 6.41 | 496.8 |
| 9 | Oklahoma | 11 | 2245 | 3137 | 888 | 5382 | 6.06 | 489.3 |
| 10 | TCU | 13 | 2194 | 3158 | 932 | 5352 | 5.74 | 411.7 |