2022 Big 12 Conference Leaders Sacks - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Oklahoma | 2 | 9.0 | 64 | 4.50 |
| 2 | Iowa State | 1 | 4.0 | 50 | 4.00 |
| 2 | Texas | 2 | 4.0 | 31 | 2.00 |
| 2 | Baylor | 3 | 4.0 | 29 | 1.33 |
| 2 | Kansas | 1 | 4.0 | 15 | 4.00 |
| 6 | TCU | 1 | 3.0 | 15 | 3.00 |
| 7 | Texas Tech | 1 | 2.0 | 16 | 2.00 |
| 7 | Oklahoma State | 1 | 2.0 | 15 | 2.00 |
| 7 | Kansas State | 1 | 2.0 | 10 | 2.00 |