2022 Atlantic Coast Conference Leaders Opponent First Downs - Games in August/September Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 4 | 18 | 32 | 5 | 55 | 13.8 |
| 1 | Miami (Florida) | 4 | 18 | 33 | 4 | 55 | 13.8 |
| 3 | Syracuse | 4 | 26 | 36 | 5 | 67 | 16.8 |
| 4 | Pittsburgh | 4 | 17 | 42 | 10 | 69 | 17.3 |
| 4 | Virginia Tech | 4 | 25 | 29 | 15 | 69 | 17.3 |
| 4 | Boston College | 4 | 27 | 36 | 6 | 69 | 17.3 |
| 7 | Wake Forest | 4 | 29 | 37 | 5 | 71 | 17.8 |
| 8 | Louisville | 4 | 35 | 31 | 7 | 73 | 18.3 |
| 9 | Clemson | 4 | 22 | 43 | 9 | 74 | 18.5 |
| 10 | Florida State | 4 | 31 | 38 | 9 | 78 | 19.5 |
| 11 | Virginia | 4 | 26 | 46 | 7 | 79 | 19.8 |
| 12 | Duke | 4 | 28 | 46 | 8 | 82 | 20.5 |
| 13 | Georgia Tech | 4 | 52 | 39 | 12 | 103 | 25.8 |
| 14 | North Carolina | 4 | 51 | 47 | 16 | 114 | 28.5 |