2022 Atlantic Coast Conference Leaders Tackles For Loss - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Clemson | 4 | 31.0 | 93 | 7.75 |
| 2 | Louisville | 3 | 24.0 | 100 | 8.00 |
| 3 | Syracuse | 4 | 21.0 | 83 | 5.25 |
| 4 | Miami (Florida) | 3 | 17.0 | 70 | 5.67 |
| 5 | Georgia Tech | 4 | 15.0 | 69 | 3.75 |
| 5 | Pittsburgh | 2 | 15.0 | 50 | 7.50 |
| 5 | North Carolina | 4 | 15.0 | 45 | 3.75 |
| 5 | Boston College | 3 | 15.0 | 32 | 5.00 |
| 9 | North Carolina State | 2 | 13.0 | 36 | 6.50 |
| 10 | Wake Forest | 2 | 12.0 | 35 | 6.00 |
| 11 | Virginia Tech | 1 | 11.0 | 26 | 11.00 |
| 12 | Florida State | 2 | 10.0 | 37 | 5.00 |
| 13 | Duke | 1 | 2.0 | 30 | 2.00 |