2022 Atlantic Coast Conference Leaders Tackles For Loss - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Louisville | 4 | 29.0 | 136 | 7.25 |
| 2 | Virginia Tech | 2 | 19.0 | 56 | 9.50 |
| 3 | Boston College | 2 | 15.0 | 51 | 7.50 |
| 4 | Wake Forest | 2 | 14.0 | 78 | 7.00 |
| 5 | Duke | 2 | 13.0 | 71 | 6.50 |
| 5 | Miami (Florida) | 2 | 13.0 | 48 | 6.50 |
| 7 | Syracuse | 2 | 12.0 | 43 | 6.00 |
| 7 | North Carolina | 3 | 12.0 | 31 | 4.00 |
| 9 | North Carolina State | 2 | 11.0 | 41 | 5.50 |
| 9 | Clemson | 2 | 11.0 | 25 | 5.50 |
| 11 | Virginia | 1 | 7.0 | 28 | 7.00 |
| 12 | Florida State | 1 | 6.0 | 21 | 6.00 |
| 12 | Georgia Tech | 1 | 6.0 | 14 | 6.00 |
| 14 | Pittsburgh | 1 | 4.0 | 18 | 4.00 |